Understanding Masculinising Hormone Therapy

Masculinising hormone therapy uses testosterone to develop physical characteristics aligned with a masculine identity. This guide explains the testosterone types Gender Journey supports and what to discuss with your healthcare provider.

Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult with your healthcare provider before making any changes to your medication.

Testosterone Types

Gender Journey tracks the following testosterone preparations:

Injectable Testosterone

• Testosterone Enanthate — Typically injected every 1–4 weeks. One of the most commonly prescribed forms.
• Testosterone Cypionate — Typically injected every 1–4 weeks. Very similar to enanthate, widely used in North America.
• Testosterone Undecanoate — A long-acting injection administered every 10–14 weeks. Requires less frequent dosing but is usually given by a healthcare professional.

Topical Testosterone

• Testosterone Gel — Applied to the skin daily. Provides steady hormone levels and is easy to adjust.
• Testosterone Patch — Applied to the skin daily. Another transdermal option that provides consistent delivery.

Choosing a Form

Your healthcare provider will recommend a form based on:

• Your preference — Some people prefer weekly injections; others prefer daily gel or patches.
• Lifestyle — Injections require less daily attention; gels and patches need consistent daily application.
• Health considerations — Certain forms may be better suited depending on your medical history.
• Availability — Not all forms are available or funded in every region.

How Testosterone Works

Testosterone drives masculinising changes by interacting with androgen receptors throughout the body. It is also partially converted to dihydrotestosterone (DHT), which influences hair growth and other androgenic effects. Regular monitoring ensures hormone levels stay within the target range.

Getting Started

1. Your healthcare provider will prescribe testosterone and explain the dosing schedule.
2. Add the medication to My Medications in Gender Journey.
3. Set reminders for each dose or injection.
4. Schedule regular blood tests — typically every 3 months for the first year, then every 6–12 months.