Understanding Feminising Hormone Therapy

Feminising hormone therapy (HRT) uses oestrogen, anti-androgens, and sometimes progestogens to develop physical characteristics aligned with a feminine identity. This guide explains the medications Gender Journey can help you track.

Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult with your healthcare provider before making any changes to your medication.

Oestrogen

Oestrogen is the primary hormone in feminising HRT. Gender Journey supports tracking the following forms:

• Estradiol (Oral) — Tablets taken daily. A common starting option, though oral forms pass through the liver.
• Estradiol (Transdermal Gel) — Applied to the skin daily. Bypasses the liver and provides steady levels.
• Estradiol (Transdermal Patch) — Changed every 3–7 days. Provides consistent delivery with minimal daily effort.
• Estradiol Valerate (Injection) — Typically administered every 1–2 weeks. Offers reliable absorption.
• Estradiol Cypionate (Injection) — Typically administered every 1–2 weeks. Another injectable option with a slightly different release profile.

Your healthcare provider will help you choose the form best suited to your health profile, lifestyle, and preferences.

Anti-Androgens

Anti-androgens reduce the effects of testosterone and are often prescribed alongside oestrogen. The app tracks:

• Spironolactone — Oral, taken daily. One of the most commonly prescribed anti-androgens.
• Cyproterone Acetate — Oral, taken daily. Widely used outside the United States (not available in the USA).
• Bicalutamide — Oral, taken daily. A newer option sometimes used as an alternative.
• Finasteride — Oral, taken daily. A 5α-reductase inhibitor that blocks the conversion of testosterone to DHT.
• Dutasteride — Oral, taken daily. Another 5α-reductase inhibitor, similar to finasteride.

Progestogens

Some feminising HRT regimens include a progestogen. Gender Journey tracks:

• Medroxyprogesterone Acetate — A synthetic progestogen.
• Micronised Progesterone — A bioidentical form of progesterone.

The role of progestogens in feminising HRT is an area of ongoing research. Discuss the potential benefits and risks with your healthcare provider.

Logging Your Medications in Gender Journey

Use the My Medications section to add each of your prescribed medications. You can set the dose, frequency, route of administration, and enable reminders so you never miss a dose. All data is stored securely and privately.